The Pasteur Station of the Ufa Province Council was officially opened on June 5, 1905. It was needed due to the high prevalence of infectious diseases among the local population, the extremely low level of health culture, a lack of preventive preparations and insufficient number of trained medicinal workers (thematic photo on the first page of the NPO’s website).
In 1906, the Bacteriological Laboratory of the Ufa Province Council consisting of the diagnostic room, the vaccine and serum department and the smallpox calf house was based on the laboratory. The head of the station was an invited bacteriologist – doctor V.N. Kryzhanosky.
Under his guidance, the laboratory started the production of smallpox detritus and – in 1907 – diphtheria and scarlet fever serums.
In 1908, the Bacteriological Laboratory was renamed the Bacteriological Institute of the Ufa Province Council.
But by 1911 it was expanded by the veterinary department and a year later by the chemical and hygienic department for sanitary and hygienic researches, which began the production of anti-dysentery and polyvalent antistreptococcal serums.
In 1913, the microbiological department was established to carry out sanitary, bacteriological, histopathological and serological studies, including the Wasserman reaction.
During the October Revolution of 1917 the Bacteriological Institute was transferred by Kolchak’s army to Omsk and until 1921 it was divided and operated in two cities.
By 1921, according to the special Decree of the Presidium of the RSFSR People's Commissariat at the request of the Ufa Executive Committee, the Bacteriological Institute was re-evacuated to Bashkiria and renamed the Sanitary and Bacteriological Institute of the Ufa Province Healthcare Department.
In 1922 the Institute became subordinated to the Bashkir People’s Healthcare Commissariat and named the Sanitary and Bacteriological Institute of the Bashkir People’s Healthcare Commissariat. The microbiological department was divided into the epidemiological and diagnostic and treatment departments.
In 1934 the Institute was renamed the Bashkir Regional Sanitary and Bacteriological Institute and expanded by the biological department and the laboratory for the local control of bacterial preparations.
During the war, due to the wartime circumstances the institute’s profile was radically changed: the production of serums was transferred to the Mechnikov Moscow Regional Institute evacuated to Ufa, and the production of vaccines, bacteriophages and diagnostic preparations was carried out by Ufa’s microbiologists.
The effective joint actions of microbiologists and physicians during the war helped to prevent tremendous epidemic outbreaks, which saved hundreds of thousands of lives.
According to the Decree of the USSR Soviet of Ministers No. 1250 dated November 13, 1952, the Ufa Scientific and Research Institute of Epidemiology and Microbiology was subordinated to the Chief Department for the Production of Bacterial and Viral Preparations of the USSR Ministry of Health and was named the I.I. Mechnikov Ufa Scientific and Research Institute of Vaccines and Serums of the USSR Ministry of Health. Serum Department of the I.I. Mechnikov Ufa Scientific and Research Institute of Vaccines and Serums of the USSR Ministry of Health, 1957
The further significant development of the institute occurred after the establishment of the Immunopreparat Scientific and Production Association on its basis in 1988.
By the middle of 1995, NPO Immunopreparat had been approved as the State Enterprise (SE) Immunopreparat Scientific and Production Association of the Ministry of Health and Medical Industry of the RF, and in 1997 SE Immunopreparat Scientific and Production Association was approved as the State Unitary Enterprise (SUE) Immunopreparat of the Ministry of Health and Medical Industry of the RF.
The manufactured products have been awarded 96 medals of the USSR Exhibition of Economic Achievements – the All-Russian Exhibition Center, 15 diplomas, 205 USSR copyright certificates and Russian patents. It has published 18 monographs and 39 collections of scientific papers. It has trained more than 20 doctors of sciences and 120 candidates of sciences.
At present, it has the staff of about 1800 employees. It produces various immunobiological preparations and medicines for the diagnosis, prevention and treatment of infectious, allergic, bodily diseases and immunity correction – antitoxic serums, vaccines and toxoids, blood products, bacteriophages, cytomedines, detoxification solutions.
For the great contribution to the development of practical healthcare and medical science the team of the Ufa branch of FSUE NPO Microgen of the Russian Ministry of Health was awarded republic, national and international awards. Leading specialists were awarded the title of distinguished physicians, chemists, scientists of Russia and Belarus, awards and medals.