The World's First Universal Bacteriophage Capsules are Developed to Combat Infections

The Scientific and Production Association Microgen of the National Immunobiological Company (part of Rostec State Corporation) has developed a universal drug product that allows one capsule to replace the intake of a complex of traditional antimicrobial agents for infectious diseases treatment. The drug targets only bacterial cells, without affecting the body flora.

It is an oral capsule containing a specialized complex of dry bacteriophages against the diseases caused by several pathogens simultaneously. This eliminates the need to take a complex of medicines for the treatment and prevention of each disease separately.

The drug action, in contrast to traditional antimicrobial agents, including antibiotics, is based on the targeted destruction of exclusively harmful cells of the pathogen. Bacteriophages do not affect the “beneficial” body flora and do not have side effects, which excludes the possibility of dysbiosis and complications in the work of vital organs: liver, kidneys, and intestines. After the destruction of pathogenic bacteria, the drug is completely excreted from the body naturally.

One capsule includes an antimicrobial bacteriophage complex for the prevention and control of a number of common bacteria. The drug has already been developed and will be marketed after necessary research and marketing authorization. At the moment, preclinical and Phase 1 clinical trials have been successfully completed, showing its safety.

The Rostec development will allow treatment and prevention of diseases caused by bacteria of the genera Staphylococcus, Streptococcus, Proteus (P. vulgaris, P. mirabilis), Klebsiella pneumoniae, as well as Pseudomonas aeruginosa and Escherichia coli.

These bacteria are the cause of a number of the ENT diseases (strep throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, and pleurisy), surgical and urinary tract infections (abscess, hidradenitis, paraproctitis, mastitis, osteomyelitis, cystitis, pyelonephritis, endometritis, and others), and various generalized septic and inflammatory diseases of the newborn.